fig1

Precision medicine in early-onset epilepsy: the KCNQ2 paradigm

Figure 1. EEG findings in the patient. A: EEG at 13 days showing multifocal epileptic abnormalities; B: EEG at 18 days shows suppression burst activity; C: EEG during sleep at 25 days after the introduction of sodium channel blockers reveals an attenuation of multifocal epileptiform abnormalities; D: EEG in wake with sporadic epileptic abnormalities and monomorphic theta-delta rhythms, combined with slow bifrontal graphoelements. All EEG shown are in a reduced montage with setting the low-frequency time constant at 0.1 seconds, high-frequency filter at 50 Hz (except in frame B where it is 15 Hz), notch filter at 50 Hz, sensitivity at 10 μV/mm (except in frame B: 14 μV/mm), paper speed is 20 sec per epoch

Journal of Translational Genetics and Genomics
ISSN 2578-5281 (Online)
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