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From: Shared genomic segment analysis in a large high-risk chronic lymphocytic leukemia pedigree implicates CXCR4 in inherited risk

Shared genomic segment analysis in a large high-risk chronic lymphocytic leukemia pedigree implicates <i>CXCR4</i> in inherited risk

Figure 2. Shared genomic segment (SGS) analysis results. (A) Manhattan plot of the genome-wide SGS optimal segment P-values. Significant threshold (μ = 0.05) is 3.98 × 10^-7. Suggestive threshold (μ = 1.0) is 2.98 × 10^-6. (B) SGS segment plot focused on the 50 Mb surrounding the significant peak at 2q22.1. The plot shows all the SGS segments and their P-values. Segments in the optimal set (segments that are the most significant P-value at a position in the genome) are highlighted in red.