fig2

Figure 2. Patient #45 (33.2 years) with moderate ABCA4-IRD with perifoveal atrophy. (A) FAF: multiple flecks with increased intensity in the macula as well as beyond the vascular arcades with peripapillary sparing, in addition to a parafoveal area of slightly increased intensity. (B) NIA: multiple flecks with reduced intensity, including the fovea and a parafoveal ring with peripapillary sparing, as well as a few flecks with slightly increased intensity. (C) W-OCT: paracentral loss of outer retinal layers corresponds to slightly increased FAF intensity (A) and a marked loss of NIA intensity (B). (D) W-OCT: near the upper temporal vascular arcade, flecks of subretinal material (SRM, blue arrow) correspond to flecks of increased FAF intensity (A) and reduced NIA intensity (B).