fig3

Figure 3. Patient #1 (29.5 years) with marked ABCA4-IRD with macular atrophy. (A) FAF: multiple flecks with mostly increased intensity in the macula as well as beyond the vascular arcades with peripapillary sparing, in addition to central flecks of reduced intensity. (B) NIA: multiple flecks with markedly reduced intensity with peripapillary sparing and no flecks with increased intensity. (C) W-OCT: central loss of outer retinal layers as well as outer retinal irregularities nasal to the optic disc corresponding to FAF lesions with increased or reduced intensity (A) as well as NIA lesions with markedly reduced intensity.