fig2

Figure 2. The population to be recruited are individuals from age 30 to 60 without known heart disease. DNA samples can be obtained from blood specimens. The DNA will be isolated and genotyped for the genetic risk variants predisposing to CAD. The genetic risk score (GRS) is calculated as a single number. Based on the GRS, the patients are stratified into three groups: high, intermediate, and low risk. Those in the high-risk group will be counseled and appropriate preventative measures will be recommended. The population will be followed annually for 10 years.