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Figure 2. The different effects of SNPs in lncRNAs. Purple stars representing SNPs. (A) If a SNP is present in enhancer/promoter regions of a lncRNA, it can affect the transcription of a lncRNA, changing the transcription factor binding sites or chromatin accessibility. (B) Splicing of a lncRNA can be affected by a SNP enhancing exon skipping. (C) Secondary and tertiary structures of lncRNAs can be modulated by the SNP genotype, mainly when they are located within an exon. Created with BioRender.com.