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    Letter to Editor| Open Access

    Gene dosage defects in primary immunodeficiencies and related disorders: a pilot study

    Lisa Dyer , Xia Li , James Denton , Brittany Jones , Emily Liston , Danielle Hilton , Abhinav Mathur , Kejian Zhang , C. Alexander Valencia J Transl Genet Genom 2017;1:23-7
    Published on: 25 Dec 2017  | Viewed:181  | Downloaded:19
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    Topic: MicroRNAs in Allergic Diseases| Open Access

    MicroRNAs in atopic dermatitis: a review

    Neeti Bhardwaj

    Atopic dermatitis (AD) is a chronic and relapsing inflammatory skin disease, generally the first clinical manifestation of atopy and the start of atopic march. Effective treatment of AD could potentially interrupt the progression of atopic march. MicroRNAs (miRNAs), a recently described class of... Read more

    J Transl Genet Genom 2017;1:15-22
    Published on: 17 Nov 2017  | Viewed:404  | Downloaded:25
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    Topic: Reversing X Chromosome Inactivation as a New Therapeutic Treatment for X-linked Diseases| Open Access

    Reversal of X chromosome inactivation: lessons from pluripotent reprogramming of mouse and human somatic cells

    Irene Cantone

    X chromosome inactivation (XCI) is a strategy used by mammals to silence genes along one of the two female X chromosomes and equilibrate expression dosage between XY males and XX females. This epigenetically-inherited silencing is established during early embryonic development and maintained... Read more

    J Transl Genet Genom 2017;1:1-14
    Published on: 16 Nov 2017  | Viewed:517  | Downloaded:20
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